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Journal of separation science

A preparative isolation and purification of arctigenin and matairesinol from Forsythia koreana by centrifugal partition chromatography.


PMID 16605084

Abstract

Centrifugal partition chromatography was applied to separate arctigenin and matairesinol from Forsythia koreana extract with a two-phase solvent system composed of n-hexane-ethyl acetate-methanol-water (5:5:5:5 v/v). Using this method, arctigenin and matairesinol were successfully separated from partially purified F. koreana extracts in only one step. The purities of isolated compounds were determined to be over 90% by HPLC analysis.

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