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Bioorganic & medicinal chemistry letters

Epibatidine isomers and analogues: structure-activity relationships.


PMID 16934977

Abstract

Binding affinities for a range of epibatidine isomers and analogues at the alpha4beta2 and alpha3beta4 nAChR subtypes are reported; compounds having similar N-N distances to epibatidine show similar, high potencies.

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