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Bioorganicheskaia khimiia

[Racemic and optically active alpha-tocopherol analogues with a modified side chain: synthesis and biological activity].


PMID 17886430

Abstract

Information on the synthesis and biological activity of natural and synthetic analogues of alpha-tocopherol with a modified side chain is systematized. These compounds are of interest as vitamin E metabolites, hydrophilic antioxidants, and precursors of drugs with combined pharmacological properties useful in therapy of pathological disorders caused by oxidative stress.