EMAIL THIS PAGE TO A FRIEND

Biosensors & bioelectronics

Biological pH sensing based on surface enhanced Raman scattering through a 2-aminothiophenol-silver probe.


PMID 17996441

Abstract

We report pH sensing for biological applications based on surface enhanced Raman scattering (SERS) from silver nanoparticles functionalized with 2-aminothiophenol (2-aminobenzenethiol, 2-ABT). pH-dependent SERS spectra of the attached 2-ABT molecules enable one to sense the pH over the range of 3.0-8.0. We have performed the first demonstration of SERS detection in living cells kept in different pH buffer solutions and show that the pH sensitivity is retained in that case. Thus, the nanoparticles can be used as probes delivering spatially localized chemical information from biological environments and provide a new way to monitor chemical changes at cellular level.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

274240
2-Aminothiophenol, 99%
C6H7NS
123137
2-Aminothiophenol, technical grade, 90%
C6H7NS