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Nucleosides, nucleotides & nucleic acids

Asymmetric synthesis of novel apio carbocyclic nucleoside analogues as potential antiviral and antitumor agent.


PMID 18066888

Abstract

Novel apio carbocyclic nucleosides 18-21 were asymmetrically synthesized as potential antiviral and antitumor agent, starting from D-ribose employing aldol reaction, RCM reaction and Mitsunobu reaction as key reactions.

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