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Journal of photochemistry and photobiology. B, Biology

Photocytotoxicity of platinum(IV)-chloride surface modified TiO2 irradiated with visible light against murine macrophages.


PMID 18555693

Abstract

Phototoxicity of titanium dioxide modified with platinum(IV)-chloride complexes, [TiO2/PtCl4], irradiated with visible light was tested on murine macrophage cell line (RAW 264.7) in vitro. Presence of antioxidants such as alpha-tocopherol or beta-carotene during photodynamic treatment significantly increased cells viability. Our results indicate that observed cell death induced by [TiO2/PtCl4] was due to photogeneration of reactive species.