EMAIL THIS PAGE TO A FRIEND

Organic letters

Protecting group free glycosidations using p-toluenesulfonohydrazide donors.


PMID 18616337

Abstract

N'-Glycopyranosylsulfonohydrazides are introduced as glycosyl donors for protecting group free synthesis of O-glycosides, glycosyl azides, and oxazolines. Mono- and disaccharides containing a reducing terminal N-acetylglucosamine residue were condensed with p-toluenesulfonylhydrazide to give the desired beta- d-pyranose donors. These donors can be activated with NBS and then glycosidated with the desired alcohol or transformed to the oxazoline or glycosyl azide.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

132004
p-Toluenesulfonyl hydrazide, 97%
C7H10N2O2S