EMAIL THIS PAGE TO A FRIEND

Journal of combinatorial chemistry

Novel and efficient one-pot tandem synthesis of 2-styryl-substituted 4(3H)-quinazolinones.


PMID 18671434

Abstract

A novel one-pot tandem synthesis of 2-styryl-4(3 H)-quinazolinones in an acidic ionic liquid is reported. In this procedure isatoic anhydride, a primary aniline or ammonium acetate, and triethylorthoacetate are reacted in the presence of imidazolium trifluoroacetate [Hmim]TFA. Subsequently an aromatic aldehyde is added to the mixture to afford the title compounds in high to excellent yields.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

I12808
Isatoic anhydride, 96%
C8H5NO3