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Agents and actions. Supplements

A new antiinflammatory agent (EGIS-5645) without gastrointestinal side-effect.


PMID 1906236

Abstract

The compound EGIS-5645 is a potent antipyretic agent possessing analgesic and antiinflammatory properties. The drug is active in antiinflammatory models such as carrageenin oedema and adjuvant arthritis. EGIS-5645 shows practically no gastro-ulcerogenic effect. The molecule does not inhibit either prostaglandin biosynthesis or soybean lipoxygenase enzyme activity.

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