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Medycyna doswiadczalna i mikrobiologia

[Activity of indolicidin, alone or together with oxacillin, against Staphylococcus aureus and S. epidermidis].


PMID 19143172

Abstract

Difficulties in the treatment of staphylococcal infections as well as the increasing frequency of isolating resistant clinical strains have prompted a search, among the products of immune systems of plants and animals, for more effective antistaphylococcal therapies. This study examined the activity of indolicidin towards the planktonic cultures and biofilm of Staphylococcus aureus and S. epidermidis strains representing different clinical sources and various profiles of drug sensitivity. The synergistic effect between the peptide and oxacilin was also studied.