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ACS chemical biology

Expanding the repertoire of fluorescent calcium sensors.


PMID 19298092

Abstract

Fluorescent indicators for calcium are incredibly powerful because they enable researchers to watch the movement of calcium ions in real time in living cells. The popular small molecule indicator Indo-1 has now been targeted to a defined location, namely, the nucleus of muscle cells, using SNAP-tag technology. This combination of a chemical probe with genetic targeting expands the available options for measuring local calcium events in cells.

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57180
Indo 1, for fluorescence, ≥80.0% (HPLC)
C32H26K5N3O12