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Hepato-gastroenterology

Perhexiline maleate-induced hepatitis.


PMID 1937378

Abstract

We report on a case of perhexiline maleate-induced hepatitis secondary to a long-term administration of recommended daily dosages of 300 mg. The patient had a spectacular weight loss of 29 kg. He developed hepatitis, which subsided after drug withdrawal. Our electron-microscopic findings with the typical inclusion bodies and impaired hydroxylation capacity point to an underlying metabolic disorder as the pathogenetic mechanism.

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SML0120
Perhexiline maleate salt, ≥98% (HPLC)
C19H35N · C4H4O4