EMAIL THIS PAGE TO A FRIEND

Combinatorial chemistry & high throughput screening

Multicomponent one-pot reactions: synthesis of some new 6-oxopyrano [2,3-c]isochromenes by condensation of homophthalic anhydride, dialkyl acetylenedicarboxylate, and isocyanides.


PMID 19519334

Abstract

A novel three-component, one-pot condensation of the zwitterion generated from dialkyl acetylenedicarboxylate and isocyanides with homophthalic anhydride is described. The reaction affords new 6-oxopyrano[2,3-c]isochromenes in good yield. Isochromenes have been reported to possess diverse biological activities such as antibacterial, antifungal, antiinflammatory, and antiangiogenic effects. Moreover, Theses important compounds are found in various natural products.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

128589
Homophthalic anhydride, technical grade
C9H6O3