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Mini reviews in medicinal chemistry

The use of intravenous aminobisphosphonates for the treatment of Paget's disease of bone.


PMID 19689402

Abstract

Paget's disease of bone is a focal skeletal disorder characterized by the formation of structurally abnormal bone, deformity and other complications leading to significant disability and bone pain. Recently, the availability of newer, more potent nitrogen-containing bisphosphonates has improved treatment outcomes, allowing a more effective and convenient management of this disorder.

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