EMAIL THIS PAGE TO A FRIEND

Chemistry (Weinheim an der Bergstrasse, Germany)

Direct ortho-arylation of N-phenacylpyridinium bromide by palladium-catalyzed C-H-bond activation.


PMID 19856343

Abstract

A novel palladium catalyzed direct ortho-arylation of N-phenacylpyridinium bromide was developed. The amazing N-phenacyl group regioselectively activates the C-H bond of pyridine and automatically departs from the arylated products. A kinetic isotope effect study proved that the reaction went through a C-H-bond activation pathway and 2,6-diphenylpyridine was produced stepwise from 2-phenylpyridine.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

P33402
2-Phenylpyridine, 98%
C11H9N