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Bulletin of experimental biology and medicine

Role of the serotoninergic system in the development of diseases of the intestinal and biliferous tracts.


PMID 19907762

Abstract

Primary sclerosing cholangitis and nonspecific ulcerative colitis were modeled before and after serotonin and spiperone injections. Activation of the serotoninergic system prevented the development of primary sclerosing cholangitis, but promoted more severe course of nonspecific ulcerative colitis.