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Bioorganic & medicinal chemistry letters

The synthesis of novel fluorescent purine analogues modified by azacrown ether at C6.


PMID 20399655

Abstract

The synthesis and fluorescence properties of novel purine analogues linked azacrown ether at C6 position were investigated. These new purine analogues could be prepared from a series of 6-chloropurines and showed selective and efficient signaling behaviors toward micromolar concentration of Ag(+) ion over other common metal ions in an aqueous environment.

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