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Eksperimental'naia i klinicheskaia farmakologiia

[Cytokine synthesis in the healthy volunteer's blood mononuclear cells under the influence of an indolyl-thio-alkanecarboxylic acid derivative with selective immunosuppressant properties].


PMID 20408426

Abstract

The influence of BM-7-02 compound on the production of cytokines in the culture of healthy volunteers' blood cells. This compound suppresses the production of main cytokine (gamma-IFN, IL-2 and IL-4) synthesized by CD4+ Th1 and Th2 cells, stimulates the production of TNF-alpha and IL-6, and does not change the production of IL-1 beta.

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