The American journal of Chinese medicine

The correlation between bioactive components of Fallopia multiflora root and environmental factors.

PMID 20503466


Fallopia multiflora (Thunb.) Harald, a traditional Chinese medicinal plant, is used in treating dizziness. In this study, the samples of F. multiflora from ten different locations were collected, and five bioactive components (2, 3, 5, 4'-tetrahydroxystilbene-2-O-beta-D-glucoside, emodin, emodin-8-O-beta-D-glucoside, physcion and physcion-8-O-beta-D-glucoside) were quantified by high performance liquid chromatography. The correlations between 17 environmental factors and 5 bioactive components were analyzed. The results showed that the highest contents of bioactive components were in samples from Deqing, and the lowest in samples from Tianyang, which indicated that the quality of F. multiflora grown in Deqing was superior, while that grown in Tianyang was inferior. Emodin content was negatively correlated with the average temperature in January (p < 0.01) and the accumulated temperature (p < 0.01). Physician content was also negatively correlated with the average temperature in January (P < 0.01), the accumulated temperature (p < 0.05) and the organic matter (p < 0.05). However, emodin was positively correlated with the soil available K (p < 0.05) and Zn (p < 0.01). The results of stepwise regression showed that the accumulated temperature was the main factor influencing the contents of emodin and physcion. However, none of the environmental factors had significant correlation with 2, 3, 5, 4'-tetrahydroxystilbene-2-O-beta-D-glucoside, emodin-8- O-beta-D-glucoside and physcion-8-O-beta-D-glucoside. In conclusion, some environmental factors have significant influence on the content of dissociated anthraquinones, while some have no influence on that of combined anthraquinones.

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Physcion, ≥98.0% (TLC)
Physcion, analytical standard