EMAIL THIS PAGE TO A FRIEND

Prikladnaia biokhimiia i mikrobiologiia

[Photobiochemistry of folates: a photochemical reduction of folic acid].


PMID 20586292

Abstract

Exposure of deaerated folic acid solutions containing an electron donor to UV radiation (310-390 nm, I = 0.4 W m(-2)) induced formation of dihydrofolic acid (DHFA), a photoexcitation which gave tetrahydrofolic acid (THFA). Only DHFA was formed in the presence of EDTA (E'o = +0.40 V), while the presence of stronger reductants-NADH (E'o = -0.32 V) and boron hydride (E'o = -0.48 V)-induced photoreduction to THFA. It was demonstrated that UV radiation had no effect on the THFA formylation, giving the coenzyme 5,10-methenyltetrahydrofolic acid and its transformation into another coenzyme, 5-formyltetrahydrofolic acid.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

D7006
Dihydrofolic acid, ≥90%
C19H21N7O6
T3125
Tetrahydrofolic acid, ≥65% (when packaged), powder
C19H23N7O6