EMAIL THIS PAGE TO A FRIEND

Molecular diversity

New multicomponent approach for the synthesis of benzo[c]coumarin derivatives over MgO under solvent-free conditions.


PMID 20652403

Abstract

In this study, a three-component one-pot synthesis of select 5-amino-6-cyano-3-hydroxybenzo[c]coumarin compounds derived from salicylaldehydes, malononitrile, and ethyl acetoacetate is reported. The reaction is conducted on grinding over MgO at room temperature resulting in good yields.