EMAIL THIS PAGE TO A FRIEND

Bioorganic & medicinal chemistry letters

Preliminary studies of 3,4-dichloroaniline amides as antiparasitic agents: structure-activity analysis of a compound library in vitro against Trichomonas vaginalis.


PMID 20667728

Abstract

Trichomonas vaginalis, a human-infectious protozoan, can display resistance to treatment by metronidazole. A library of 3,4-dichloroaniline amides based on propanil, an herbicide, has been synthesized and screened to test susceptibility to these analogs. From this preliminary study, the most effective compound 15, inhibits growth of the organism by 66% and 69% on the two strains tested, T1 and G3, respectively.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

23290
Chloranil, purum, ≥97.0% (AT)
C6Cl4O2
232017
Tetrachloro-1,4-benzoquinone, 99%
C6Cl4O2