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The Journal of organic chemistry

Synthesis of indolequinones from bromoquinones and enamines mediated by Cu(OAc)2.H2O.


PMID 20690687

Abstract

A Cu(II)-mediated synthesis of indolequinones from the corresponding bromoquinones and enamines is reported. The key oxidative cyclization proceeds in good yield for a broad range of substrates and can be performed on a multigram scale, allowing access to biologically interesting structures.

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