EMAIL THIS PAGE TO A FRIEND

Chemistry (Weinheim an der Bergstrasse, Germany)

Integrated palladium-catalyzed arylation of heavier Group 14 hydrides.


PMID 21031364

Abstract

A convenient procedure has been developed for the preparation of Group 14 compounds by integrated palladium-catalyzed cross-coupling of aromatic iodides with the corresponding Group 14 hydrides in the presence of a base. The reaction conditions can be applied to the cross-coupling of tertiary, secondary, and primary Group 14 compounds. In most cases, the desired arylated products were obtained in synthetically useful yields. Even in the case of aryl iodides containing OH, NH(2), CN, or CO(2)R groups, the reactions proceeded with good to high yields with tolerance of these reactive functional groups. A possible application of this method is the unique synthesis of a fungicidal diarylmethyl(1H-1,2,4-triazol-1-ylmethyl)silane derivative.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

45753
Flusilazole, PESTANAL®, analytical standard
C16H15F2N3Si
PS2041
Flusilazole, analytical standard
C16H15F2N3Si