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Chemical communications (Cambridge, England)

Synthesis of 3-indole derivatives by copper sulfonato Salen catalyzed three-component reactions in water.


PMID 21340052

Abstract

An efficient three-component reaction of indole, aldehyde, and malononitrile in water catalyzed by a copper(II) sulfonato Salen complex afforded 3-indole derivatives in good to excellent yields up to 97%.

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