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Organic letters

Synthetic studies on indolocarbazoles: total synthesis of staurosporine aglycon.


PMID 21341756

Abstract

A synthesis of staurosporine aglycon and its analogs was achieved in a 28-36% overall yield starting from 2-methylindole. The prominent key steps for the synthesis of the indolocarbazole alkaloids involved electrocyclization and nitrene insertion reactions.