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The Journal of organic chemistry

Copper-catalyzed amidation of 2-phenylpyridine with oxygen as the terminal oxidant.


PMID 21401207

Abstract

The Cu(OAc)(2)-catalyzed, O(2)-mediated amidation of 2-phenylpyridine via C-H bond activation is reported. A variety of nitrogen reagents including sulfonamides, carboxamides, and anilines participate in the reaction in moderate to good yields.

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