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Zhong yao cai = Zhongyaocai = Journal of Chinese medicinal materials

[Study on the chemical constitutes of submerged cultivation mycelium of Cordyceps jiangxiensis].


PMID 21548364

Abstract

In an effort to investigate the chemical constitutes of submerged cultivation mycelium of Cordyceps jiangxiensis anamorph. The mycelia of C. jiangxiensis anamorph produced by submerged cultivation technique were separated and purified using various chromatographic techniques such as repeated liquid column chromatography, preparative thin layer chromatography etc. , and then the chemical structures of compounds obtained were elucidated on the basis of physicochemical analysis and spectroscopic techniques such as 1H-NMR, 13C-NMR and MS. Nine compounds were obtained from the petroleum ether and ethyl acetate extractive fractions of mycelial methanol extract, and were identified as follows: uracil (I), adenine (II), adenosine (III), uridine (IV), 3'-methoxyuridine (V), succinic acid (VI), nicotinic acid (VII), 1-monostearin (VIII), tetracosanoic acid (IX). Chemical constitutes of C. jiangxiensis anamorph are systematically separated for the first time, and compounds V, VII, VIII, and IX obtained are separated from Cordyceps species firstly.

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