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Natural product research

Thujone corrects cholesterol and triglyceride profiles in diabetic rat model.


PMID 21740283

Abstract

Thujone, which is the major constituent in Salvia sp. (Lamiaceae), was found to correct the lipid profile (cholesterol and triglycerides) in diabetic rats. Oral treatment with thujone (5 mg kg⁻¹ body weight dose) significantly adjusted cholesterol and triglyceride levels in diabetic rats (p ≤ 0.05) to normal levels compared to diabetic untreated rats. This provides a premise in the field of finding new agents to treat diabetic complications.

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89231
(−)-α-Thujone, ≥96.0% (GC)
C10H16O