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Klinicheskaia meditsina

[Peculiarities of ECG in patients with phenothiazine-induced cardiomyopathy].


PMID 21932558

Abstract

Ten most common and clinically significant pathological changes of ECG in schizophrenic patients with and without phenothiazine-induced cardiomyopathy (PCMP) at different stages of neuroleptic therapy are considered. A total of 46 men and 10 women were available for observation. The results of ECG studies in schizophrenics with PCMP and psychically healthy patients with DCMP were virtually identical. Dynamics of certain characteristics was shown to be of value for early diagnostics of phenothiazine cardiotoxic side-effects. These data confirm the advisability of regarding PCMP as a separate nosological entity in the group of seconfary cardiomyopathies.