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Chemical communications (Cambridge, England)

Exonuclease-assisted cascaded recycling amplification for label-free detection of DNA.


PMID 22143422

Abstract

The network consisting of three kinds of unlabeled stem-loop DNA molecular beacons (MBs) is activated by target DNA in the presence of exonuclease-III (Exo-III), achieving the concept of exonuclease-assisted cascaded recycling amplification (Exo-CRA) for DNA detection with a wide dynamic range of 8 orders of magnitude.

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