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Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology

Hearing levels in menopausal women and the effect of tibolone on audiological functions.


PMID 22369408

Abstract

The aim of this study was to examine the hearing levels of menopausal and premenopausal women of the same age and to evaluate the effect of tibolone on hearing. The study involved 83 postmenopausal women. Cases using tibolone were grouped into the tibolone group (T-group) and women without any hormone therapy were grouped into the non-tibolone group (NT-group). A total of 45 premenopausal women of the same age were taken as controls. Hearing levels of both ears were measured by audiometry. Significantly lower levels of hearing threshold at different levels were detected in the control group compared with the other groups. Postmenopausal women with and without tibolone therapy have poorer thresholds compared with still menstruating women of the same age. Thus, intrinsic oestrogen at physiological levels might slow down hearing loss in ageing women. Tibolone had no negative effect on hearing function.

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Y0000668 Tibolone for system suitability, European Pharmacopoeia (EP) Reference Standard
C21H28O2