EMAIL THIS PAGE TO A FRIEND

Organic letters

Highly efficient synthesis of N-substituted isoindolinones and phthalazinones using Pt nanowires as catalysts.


PMID 22420427

Abstract

A series of N-substituted isoindolinones have been successfully synthesized through the reductive C-N coupling and intramolecular amidation of 2-carboxybenzaldehyde and amines. This one-pot synthesis gives excellent yields using ultrathin Pt nanowires as catalysts under 1 bar of hydrogen. These unsupported catalysts can also be used for the synthesis of phthalazinones in high yield when hydrazine or phenyl hydrazine is used instead of amines.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

116017
2-Carboxybenzaldehyde, 97%
C8H6O3