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Chemical communications (Cambridge, England)

An efficient synthetic approach to 6,5'-(S)- and 6,5'-(R)-cyclouridine.


PMID 22531603

Abstract

Here we present new routes for the efficient syntheses of 6,5'-(S)- and 6,5'-(R)-cyclouridine. The syntheses utilize readily accessible uridine as a starting material. This route to the R diastereomer is significantly more efficient than previous synthetic efforts, allowing us to obtain large amounts of pure material for future biological testing.

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324442
O2,2′-Cyclouridine, 99%
C9H10N2O5