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Advances in gerontology = Uspekhi gerontologii

[Metabolic disorders in elderly patients with hypertension and their correction with melatonin].


PMID 22708450

Abstract

The incidence of dysmetabolic factors in 100 elderly patients with hypertension stage II and the role of melatoninproducing function of epiphysis (pineal gland) in the development of these disorders were studied. It was found that the decrease of melatoninproducing function is one of the factors causing disorders of carbohydrate and lipid metabolism in elderly patients with hypertension. Simultaneous application of Melatonin with lisinopril or amlodipine have the normalizing effect on metabolic parameters affected in patients with arterial hypertension.

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H0627
6-Hydroxymelatonin
C13H16N2O3