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Methods in molecular biology (Clifton, N.J.)

Synthesis and functionalization of CdSe/ZnS QDs using the successive ion layer adsorption reaction and mercaptopropionic acid phase transfer methods.


PMID 22791429

Abstract

Detailed protocols for the preparation of CdSe nanocrystals coated with a multishell structure of ZnS and their surface modification based on the successive ion layer adsorption and reaction method are described. The first phase of the synthesis produces a hydrophobic surface consisting of a TOPO/HDA ligand mixture. This is followed by a surface modification of the quantum dots (QDs) with 3-mercaptopropionic acid by the phase transfer method. The modified QDs become soluble in aqueous systems such as water or buffers for further biological applications.

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