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Bulletin of experimental biology and medicine

Chromatographic determination of methyl glyoxal in blood plasma as the test for glycotoxicity and accumulation of glycation end-products.


PMID 22808508

Abstract

We developed a method of measuring methyl glyoxal concentration in blood serum using HPLC with UV detection. Methyl glyoxal concentration was determined in healthy subjects. The method was developed for indirect but reliable measurement of the levels of glycation end-products in patients with diabetes, hyperlipidemia, and cardiovascular pathologies.