EMAIL THIS PAGE TO A FRIEND

Chemical communications (Cambridge, England)

Total synthesis of ascididemin via anionic cascade ring closure.


PMID 22864261

Abstract

A new and convergent synthesis of ascididemin is presented. Using an anionic cascade ring closure as the key step, this natural product is obtained in 45% overall yield in just 6 steps starting from 2'-fluoroacetophenone. This new approach was extended to the synthesis of a new isomer of ascididemin.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

183717
2′-Fluoroacetophenone, 97%
C8H7FO
548030
3-Bromo-4-methylpyridine, 96%
C6H6BrN