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Organic & biomolecular chemistry

Conformational modulation of Ant-Pro oligomers using chirality alteration of proline residues.


PMID 23001178

Abstract

Structural modulation of Ant-Pro (anthranilic acid-proline) oligomers has been carried out by chirality alteration of the proline residues. The results suggest that the chirality altered oligomers show well-defined helical conformation featuring nine-membered hydrogen bonding interactions - without compromising conformational rigidity.