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Journal of pediatric hematology/oncology

Life-threatening agranulocytosis, anemia, and plasmacytosis after dipyrone use for fever in a child.


PMID 23007418

Abstract

Dipyrone or metamizole Na (Novalgin) is commonly used as an antipyretic, analgesic, and spasmolytic agent in some parts of the world; however, it is banned in developed countries because of severe side effects. Here we present a case of a 4-year-old boy who developed life-threatening agranulocytosis, anemia, and marked plasmacytosis in his bone marrow after dipyrone use for fever, which resolved with steroid therapy.