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Bulletin of experimental biology and medicine

Effect of opioid peptides on the content of LPO products and antioxidant enzyme activity in the liver of rats after restraint stress.


PMID 23113295

Abstract

Administration of opioid peptides dynorphin A (1-13) and DSLET was followed by a decrease in the stress-induced activation of LPO and increase in SOD activity in the liver tissue of rats. DAGO produced a similar, but less pronounced effect. The observed changes can be related to a specific distribution of opioid receptors in the liver tissue and stress-limiting influence of these peptides in the whole body.