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Advanced healthcare materials

Cascaded photoinduced drug delivery to cells from multifunctional core-shell mesoporous silica.


PMID 23184746

Abstract

Different bioactive molecules are released into living cells from lipid-covered mesoporous silica nanoparticles. The release is triggered by light, as the particles feature covalently attached photosensitizers as membrane-opening agents. It is demonstrated that the particles achieve endosomal escape and that they release their cargo into the cytosol.

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258385
Protoporphyrin IX disodium salt, ≥90% (HPLC)
C34H32N4Na2O4