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Advanced healthcare materials

Mimicking the biological ligand-receptor principle for universal target gene delivery mediated by avidin-biotin interaction.


PMID 23184873

Abstract

A facile and flexible targeting gene-delivery strategy is reported by mimicking the biological ligand-receptor principle based on avidin-biotin interaction. In vitro and in vivo investigations demonstrate that this strategy provides a simple, but universal alternative for potential target gene delivery as well as drug delivery.

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