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Analytica chimica acta

Visual detection of arginine based on the unique guanidino group-induced aggregation of gold nanoparticles.


PMID 23374218

Abstract

A simple, cost-effective and rapid method for visual detection of arginine based on the citrate-capped gold nanoparticles (AuNPs) aggregation has been developed in this paper. Arginine is the only amino acid with guanidino group, and has the highest isoelectric point (pI) at about 10.8. At pH 9.62, negatively charged citrate-capped AuNPs are well dispersed because of strong electrostatic repulsion. However, positively charged arginine (pH

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