EMAIL THIS PAGE TO A FRIEND

Chemical communications (Cambridge, England)

Multifunctionalization of alkenes via aerobic oxynitration and sp3 C-H oxidation.


PMID 23396373

Abstract

A method for direct functionalization of three positions including an unactivated C-H bond of aliphatic alkenes using tert-butyl nitrite and molecular oxygen to give γ-lactols has been developed. The present reaction proceeds through a sequence of radical processes involving oxynitration followed by aerobic oxidation of an sp(3) C-H bond. This multifunctionalization reaction requires neither metallic reagents nor photolysis and proceeds under mild conditions.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

226637
Butyl nitrite, 95%
C4H9NO2