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Medecine sciences : M/S

[Is resilience an epigenetic phenomenon?].


PMID 23544388

Abstract

The likelihood of adult psychiatric problems is increased by childhood trauma, particularly so in carriers of certain alleles of certain genes. I discuss here a recent paper that sheds light on the mechanism of this effect, showing that specific demethylation occurring at the time of the initial trauma persists at adulthood and induces an increased reactivity to stress.