EMAIL THIS PAGE TO A FRIEND

Biomeditsinskaia khimiia

[Oxidised dextrans influence on reactive oxygen species generation by murine peritoneal exudate phagocytic cells].


PMID 23650725

Abstract

The effects of oxidized dextrans of different molecular weight on reactive oxygen species production and transmembrane mitochondrial potential of macrophages and neutrophils have been studied in vivo and in vitro. Oxidised dextrans demonstrated moderate direct antioxidant ability but induced intracellular oxidative stress through the increase of oxygen radical generation. This effect of the investigated compounds amplifies the cytotoxic and bactericidal potential of phagocytes and can influence isoniazid metabolism, thus increasing its efficiency in therapy of infectious diseases.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

00268 Dextran, analytical standard, for GPC, 1,000
00269 Dextran, analytical standard, for GPC, 5,000
00270 Dextran, analytical standard, for GPC, 12,000
00271 Dextran, analytical standard, for GPC, 25,000
00891 Dextran, analytical standard, for GPC, 50,000
00892 Dextran, analytical standard, for GPC, 80,000
00893 Dextran, analytical standard, for GPC, 150,000
00894 Dextran, analytical standard, for GPC, 270,000
00895 Dextran, analytical standard, for GPC, 410,000
00896 Dextran, analytical standard, for GPC, 670,000
31394 Dextran, enzymatic synth.
31430 Dextran, analytical standard, for GPC, Set Mp 1,000-400,000
31416 Dextran from Leuconostoc mesenteroides, analytical standard, for GPC, Mw 1,000
31417 Dextran from Leuconostoc mesenteroides, analytical standard, for GPC, Mw 5,000
D9260
Dextran from Leuconostoc mesenteroides, average mol wt 9,000-11,000
31418 Dextran from Leuconostoc mesenteroides, analytical standard, for GPC, Mw 12,000
D4626 Dextran from Leuconostoc mesenteroides, average mol wt 15,000-30,000
31419 Dextran from Leuconostoc mesenteroides, analytical standard, for GPC, Mw 25,000
D1662
Dextran from Leuconostoc mesenteroides, average mol wt 35,000-45,000
31420 Dextran from Leuconostoc mesenteroides, analytical standard, for GPC, Mw 50,000
D3759 Dextran from Leuconostoc mesenteroides, average mol wt 48,000-90,000
31421 Dextran from Leuconostoc mesenteroides, analytical standard, for GPC, Mw 80,000
D4876
Dextran from Leuconostoc mesenteroides, average mol wt 150,000
31422 Dextran from Leuconostoc mesenteroides, analytical standard, for GPC, Mw 150,000
31423 Dextran from Leuconostoc mesenteroides, for GPC, Mw 270,000
31424 Dextran from Leuconostoc mesenteroides, analytical standard, for GPC, Mw 410,000
31425 Dextran from Leuconostoc mesenteroides, analytical standard, for GPC, Mw 670,000
D5376
Dextran from Leuconostoc mesenteroides, average mol wt 1,500,000-2,800,000
31397 Dextran from Leuconostoc mesenteroides, Mr ~60,000
31398 Dextran from Leuconostoc mesenteroides, Mr ~200,000