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American journal of dentistry

Stannous fluoride dentifrices.


PMID 23833912

Abstract

Stannous fluoride has a long history of use in the improvement of oral health, and was the fluoride source first proven to provide anti-caries benefits when delivered from a dentrifrice formulation. This paper provides an account of the early use of stannous fluoride, primarily for an anti-caries benefit, and the subsequent attempts to formulate stannous fluoride into stable formulations where additional benefits of the stannous cation can be realized.