EMAIL THIS PAGE TO A FRIEND

Biomeditsinskaia khimiia

[Carbohydrates metabolism disturbances when simulating prenatal alcohol intoxication].


PMID 24479342

Abstract

The influence of prenatal alcohol intoxication on carbohydrate metabolism markers has been investigated at different terms of postnatal offspring development (15, 30 and 60 days). Plasma glucose decreased as compared with the same in control group was detected. In the liver homogenates an increase of phosphorylase activity and a decrease of glucose-6-phosphatase, aldolase and glucose-6-phosphate dehydrogenase activities were found. These changes were accompanied by the incease in the lactate/pyruvate index attributed to increased lactate content in the liver tissue. The obtained data indicate essential disturbances of carbohydrate metabolism markers in prenatal alcoholized offspring, which include stable hypoglycemia, suppression of glycolytic and pentosephosphate pathways of glucose metabolism and lactate accumulation in the liver.

Related Materials

Product #

Image

Description

Molecular Formula

Add to Cart

A8811 Aldolase from rabbit muscle, ammonium sulfate suspension, 10-20 units/mg protein
A2714 Aldolase from rabbit muscle, lyophilized powder, ≥8.0 units/mg protein
G5758 Glucose-6-Phosphatase from rabbit liver, ≥0.05 units/mg protein, Protein ~30 % (balance mostly sucrose)
G6378 Glucose-6-phosphate Dehydrogenase from baker's yeast (S. cerevisiae), Type XV, lyophilized powder, 200-400 units/mg protein (modified Warburg-Christian)
G7877 Glucose-6-phosphate Dehydrogenase from baker's yeast (S. cerevisiae), Type VII, ammonium sulfate suspension, ≥200 units/mg protein
G4134 Glucose-6-phosphate Dehydrogenase from baker's yeast (S. cerevisiae), Type IX, lyophilized powder, 200-400 units/mg protein (modified Warburg-Christian)
G5885 Glucose-6-phosphate Dehydrogenase from Leuconostoc mesenteroides, lyophilized powder, 550-1,100 units/mg protein (biuret)
G8404 Glucose-6-phosphate Dehydrogenase from Leuconostoc mesenteroides, recombinant, expressed in E. coli, ammonium sulfate suspension, 550-1,100 units/mg protein (biuret)
G5760 Glucose-6-phosphate Dehydrogenase from Leuconostoc mesenteroides, Type XXIII, ammonium sulfate suspension, 550-1,100 units/mg protein (biuret), ≥2.0 mg/mL Biuret
G8529 Glucose-6-phosphate Dehydrogenase from Leuconostoc mesenteroides, recombinant, expressed in E. coli, lyophilized powder, 550-1,100 units/mg protein (biuret)