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Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego

[Diabetes mellitus-related oxidative stress and its parameters in saliva].


PMID 24575653

Abstract

The uncontrolled accumulation of glucose and fatty acids in the human body without the possibility of any cells utilizing them as metabolic substrates is a typical occurrence in the process of diabetes mellitus. High concentration of mentioned substances leads to oxidative stress and that reasons in numerous complications as a result of diabetes which are often demonstrated in the oral cavity as periodontal inflammations. There are many ways to study the biomarkers of oxidative stress such as: superoxide dismutase (SOD), catalase, glutathione peroxidase, glutathione reductase, glutathione, vitamins, lipid peroxidation, concentration of nitrites, non-enzymatic glycosylation of proteins and hyperglycaemia in diabetes. Considering the attainability and simplicity required to collect, saliva is a popular research material used to test these biomarkers.

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